Ca(2+) permeation and/or binding to Ca(V)1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function

BACKGROUND: Ca(2+) influx through Ca(V)1.1 is not required for skeletal muscle excitation-contraction coupling, but whether Ca(2+) permeation through Ca(V)1.1 during sustained muscle activity plays a functional role in mammalian skeletal muscle has not been assessed. METHODS: We generated a mouse wi...

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Detalhes bibliográficos
Publicado no:Skelet Muscle
Main Authors: Lee, Chang Seok, Dagnino-Acosta, Adan, Yarotskyy, Viktor, Hanna, Amy, Lyfenko, Alla, Knoblauch, Mark, Georgiou, Dimitra K, Poché, Ross A, Swank, Michael W, Long, Cheng, Ismailov, Iskander I, Lanner, Johanna, Tran, Ted, Dong, KeKe, Rodney, George G, Dickinson, Mary E, Beeton, Christine, Zhang, Pumin, Dirksen, Robert T, Hamilton, Susan L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340672/
https://ncbi.nlm.nih.gov/pubmed/25717360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-014-0027-1
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