The atypical chemokine receptor ACKR2 suppresses Th17 responses to protein autoantigens

Chemokine-directed leukocyte migration is a critical component of all innate and adaptive immune responses. The atypical chemokine receptor ACKR2 is expressed by lymphatic endothelial cells and scavenges pro-inflammatory CC chemokines to indirectly subdue leukocyte migration. This contributes to the...

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Veröffentlicht in:Immunol Cell Biol
Hauptverfasser: Hansell, Chris AH, MacLellan, Lindsay M, Oldham, Rachel S, Doonan, James, Chapple, Katie J, Anderson, Elinor JR, Linington, Christopher, McInnes, Iain B, Nibbs, Robert JB, Goodyear, Carl S
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340511/
https://ncbi.nlm.nih.gov/pubmed/25348934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2014.90
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