Pharmacogenomic knowledge representation, reasoning and genome-based clinical decision support based on OWL 2 DL ontologies

BACKGROUND: Every year, hundreds of thousands of patients experience treatment failure or adverse drug reactions (ADRs), many of which could be prevented by pharmacogenomic testing. However, the primary knowledge needed for clinical pharmacogenomics is currently dispersed over disparate data structu...

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Publicat a:BMC Med Inform Decis Mak
Autors principals: Samwald, Matthias, Miñarro Giménez, Jose Antonio, Boyce, Richard D, Freimuth, Robert R, Adlassnig, Klaus-Peter, Dumontier, Michel
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340468/
https://ncbi.nlm.nih.gov/pubmed/25880555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12911-015-0130-1
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