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Pharmacogenomic knowledge representation, reasoning and genome-based clinical decision support based on OWL 2 DL ontologies

BACKGROUND: Every year, hundreds of thousands of patients experience treatment failure or adverse drug reactions (ADRs), many of which could be prevented by pharmacogenomic testing. However, the primary knowledge needed for clinical pharmacogenomics is currently dispersed over disparate data structu...

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Bibliografische gegevens
Gepubliceerd in:BMC Med Inform Decis Mak
Hoofdauteurs: Samwald, Matthias, Miñarro Giménez, Jose Antonio, Boyce, Richard D, Freimuth, Robert R, Adlassnig, Klaus-Peter, Dumontier, Michel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340468/
https://ncbi.nlm.nih.gov/pubmed/25880555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12911-015-0130-1
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