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Pharmacogenomic knowledge representation, reasoning and genome-based clinical decision support based on OWL 2 DL ontologies

BACKGROUND: Every year, hundreds of thousands of patients experience treatment failure or adverse drug reactions (ADRs), many of which could be prevented by pharmacogenomic testing. However, the primary knowledge needed for clinical pharmacogenomics is currently dispersed over disparate data structu...

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Detalhes bibliográficos
Publicado no:BMC Med Inform Decis Mak
Main Authors: Samwald, Matthias, Miñarro Giménez, Jose Antonio, Boyce, Richard D, Freimuth, Robert R, Adlassnig, Klaus-Peter, Dumontier, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340468/
https://ncbi.nlm.nih.gov/pubmed/25880555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12911-015-0130-1
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