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Role of PD-1 co-inhibitory pathway in HIV infection and potential therapeutic options
Virus-specific CD8(+) T cells play an important role in controlling viral infections including human immunodeficiency virus (HIV) infection. However, during chronic HIV infection, virus-specific CD8(+) T cells undergo functional exhaustion, lose effector functions and fail to control viral infection...
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| Veröffentlicht in: | Retrovirology |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4340294/ https://ncbi.nlm.nih.gov/pubmed/25756928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0144-x |
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