Hydrophobicity of protein determinants influences the recognition of substrates by EDEM1 and EDEM2 in human cells

BACKGROUND: EDEM1 and EDEM2 are crucial regulators of the endoplasmic reticulum (ER)-associated degradation (ERAD) that extracts misfolded glycoproteins from the calnexin chaperone system. The degradation of ERAD substrates involves mannose trimming of N-linked glycans; however the precise mechanism...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:BMC Cell Biol
Egile Nagusiak: Sokołowska, Iwona, Piłka, Ewa S, Sandvig, Kirsten, Węgrzyn, Grzegorz, Słomińska-Wojewódzka, Monika
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340280/
https://ncbi.nlm.nih.gov/pubmed/25655076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-015-0047-7
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak