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EDEM Is Involved in Retrotranslocation of Ricin from the Endoplasmic Reticulum to the Cytosol

The plant toxin ricin is transported retrogradely from the cell surface to the endoplasmic reticulum (ER) from where the enzymatically active part is retrotranslocated to the cytosol, presumably by the same mechanism as used by misfolded proteins. The ER degradation enhancing α-mannosidase I-like pr...

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Hlavní autoři: Slominska-Wojewodzka, Monika, Gregers, Tone F., Wälchli, Sébastien, Sandvig, Kirsten
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1415288/
https://ncbi.nlm.nih.gov/pubmed/16452630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-10-0961
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