BiP Negatively Affects Ricin Transport

The AB plant toxin ricin binds both glycoproteins and glycolipids at the cell surface via its B subunit. After binding, ricin is endocytosed and then transported retrogradely through the Golgi to the endoplasmic reticulum (ER). In the ER, the A subunit is retrotranslocated to the cytosol in a chaper...

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Bibliographic Details
Main Authors: Gregers, Tone F., Skånland, Sigrid S., Wälchli, Sébastien, Bakke, Oddmund, Sandvig, Kirsten
Format: Artigo
Language:Inglês
Published: MDPI 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709273/
https://ncbi.nlm.nih.gov/pubmed/23666197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins5050969
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