The Mitogen-activated Protein Kinase p38 Links Shiga Toxin-dependent Signaling and Trafficking

Shiga toxin (Stx) binds to the cell, and it is transported via endosomes and the Golgi apparatus to the endoplasmic reticulum and cytosol, where it exerts its toxic effect. We have recently shown that Stx activates the tyrosine kinase Syk, which in turn induces clathrin phosphorylation and up-regula...

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Autors principals: Wälchli, Sébastien, Skånland, Sigrid S., Gregers, Tone F., Lauvrak, Silje U., Torgersen, Maria L., Ying, Ming, Kuroda, Shun'ichi, Maturana, Andrés, Sandvig, Kirsten
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2008
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174185/
https://ncbi.nlm.nih.gov/pubmed/17959827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-06-0565
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