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Shiga Toxin Regulates Its Entry in a Syk-dependent Manner

Shiga toxin (Stx) is composed of an A-moiety that inhibits protein synthesis after translocation into the cytosol, and a B-moiety that binds to Gb3 at the cell surface and mediates endocytosis of the toxin. After endocytosis, Stx is transported retrogradely to the endoplasmic reticulum, and then the...

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Detalhes bibliográficos
Main Authors: Lauvrak, Silje Ugland, Wälchli, Sébastien, Iversen, Tore-Geir, Slagsvold, Hege Holte, Torgersen, Maria Lyngaas, Spilsberg, Bjørn, Sandvig, Kirsten
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1382301/
https://ncbi.nlm.nih.gov/pubmed/16371508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-08-0766
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