Role of homocysteinylation of ACE in endothelial dysfunction of arteries

The direct impact of de novo synthesis of homocysteine (Hcy) and its reactive metabolites, Hcy-S-S-Hcy and Hcy thiolactone (HCTL), on vascular function has not been fully elucidated. We hypothesized that Hcy synthesized within endothelial cells affects activity of angiotensin-converting enzyme (ACE)...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Huang, An, Pinto, John T., Froogh, Ghezal, Kandhi, Sharath, Qin, Jun, Wolin, Michael S., Hintze, Thomas H., Sun, Dong
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Vascular Biology and Microcirculation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340149/
https://ncbi.nlm.nih.gov/pubmed/25416191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00577.2014
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