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Role of homocysteinylation of ACE in endothelial dysfunction of arteries

The direct impact of de novo synthesis of homocysteine (Hcy) and its reactive metabolites, Hcy-S-S-Hcy and Hcy thiolactone (HCTL), on vascular function has not been fully elucidated. We hypothesized that Hcy synthesized within endothelial cells affects activity of angiotensin-converting enzyme (ACE)...

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Bibliografski detalji
Izdano u:Am J Physiol Heart Circ Physiol
Glavni autori: Huang, An, Pinto, John T., Froogh, Ghezal, Kandhi, Sharath, Qin, Jun, Wolin, Michael S., Hintze, Thomas H., Sun, Dong
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340149/
https://ncbi.nlm.nih.gov/pubmed/25416191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00577.2014
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