Chloramphenicol Restores Sigma Factor Activity to Sporulating Bacillus subtilis

The σ subunit of RNA polymerase from sporulating Bacillus subtilis is markedly inhibited in its ability to direct active transcription of phage ϕe DNA in vitro. Treatment of sporulating bacteria with chloramphenicol rapidly restores σ activity, suggesting that sporulating cells contain an inhibitor...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Segall, Jacqueline, Tjian, Robert, Pero, Janice, Losick, Richard
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1974
Materias:	Biological Sciences: Biochemistry
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433998/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4216024/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.12.4860
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