Chloramphenicol Restores Sigma Factor Activity to Sporulating Bacillus subtilis

The σ subunit of RNA polymerase from sporulating Bacillus subtilis is markedly inhibited in its ability to direct active transcription of phage ϕe DNA in vitro. Treatment of sporulating bacteria with chloramphenicol rapidly restores σ activity, suggesting that sporulating cells contain an inhibitor...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Segall, Jacqueline, Tjian, Robert, Pero, Janice, Losick, Richard
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1974
Sujets:	Biological Sciences: Biochemistry
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433998/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4216024/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.12.4860
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