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Chloramphenicol Restores Sigma Factor Activity to Sporulating Bacillus subtilis

The σ subunit of RNA polymerase from sporulating Bacillus subtilis is markedly inhibited in its ability to direct active transcription of phage ϕe DNA in vitro. Treatment of sporulating bacteria with chloramphenicol rapidly restores σ activity, suggesting that sporulating cells contain an inhibitor...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Segall, Jacqueline, Tjian, Robert, Pero, Janice, Losick, Richard
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1974
Fag:
Biological Sciences: Biochemistry
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433998/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4216024/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.12.4860
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