A Comparison of Methods for Treatment Selection in Seamless Phase II/III Clinical Trials Incorporating Information on Short-Term Endpoints

In an adaptive seamless phase II/III clinical trial interim analysis, data are used for treatment selection, enabling resources to be focused on comparison of more effective treatment(s) with a control. In this paper, we compare two methods recently proposed to enable use of short-term endpoint data...

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Detaylı Bibliyografya
Yayımlandı:J Biopharm Stat
Asıl Yazarlar: Kunz, Cornelia Ursula, Friede, Tim, Parsons, Nicholas, Todd, Susan, Stallard, Nigel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2015
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339952/
https://ncbi.nlm.nih.gov/pubmed/24697322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2013.840646
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