An Atypical Human Induced Pluripotent Stem Cell Line With a Complex, Stable, and Balanced Genomic Rearrangement Including a Large De Novo 1q Uniparental Disomy

Human induced pluripotent stem cells (hiPSCs) hold great promise for cell therapy through their use as vital tools for regenerative and personalized medicine. However, the genomic integrity of hiPSCs still raises some concern and is one of the barriers limiting their use in clinical applications. Nu...

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Bibliografski detalji
Izdano u:Stem Cells Transl Med
Glavni autori: Steichen, Clara, Maluenda, Jérôme, Tosca, Lucie, Luce, Eléanor, Pineau, Dominique, Dianat, Noushin, Hannoun, Zara, Tachdjian, Gérard, Melki, Judith, Dubart-Kupperschmitt, Anne
Format: Artigo
Jezik:Inglês
Izdano: AlphaMed Press 2015
Teme:
Pluripotent Stem Cells
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339852/
https://ncbi.nlm.nih.gov/pubmed/25650439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2014-0186
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