An Atypical Human Induced Pluripotent Stem Cell Line With a Complex, Stable, and Balanced Genomic Rearrangement Including a Large De Novo 1q Uniparental Disomy

Human induced pluripotent stem cells (hiPSCs) hold great promise for cell therapy through their use as vital tools for regenerative and personalized medicine. However, the genomic integrity of hiPSCs still raises some concern and is one of the barriers limiting their use in clinical applications. Nu...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Steichen, Clara, Maluenda, Jérôme, Tosca, Lucie, Luce, Eléanor, Pineau, Dominique, Dianat, Noushin, Hannoun, Zara, Tachdjian, Gérard, Melki, Judith, Dubart-Kupperschmitt, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2015
Assuntos:
Pluripotent Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339852/
https://ncbi.nlm.nih.gov/pubmed/25650439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2014-0186
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