An Atypical Human Induced Pluripotent Stem Cell Line With a Complex, Stable, and Balanced Genomic Rearrangement Including a Large De Novo 1q Uniparental Disomy

Human induced pluripotent stem cells (hiPSCs) hold great promise for cell therapy through their use as vital tools for regenerative and personalized medicine. However, the genomic integrity of hiPSCs still raises some concern and is one of the barriers limiting their use in clinical applications. Nu...

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Dades bibliogràfiques
Publicat a:Stem Cells Transl Med
Autors principals: Steichen, Clara, Maluenda, Jérôme, Tosca, Lucie, Luce, Eléanor, Pineau, Dominique, Dianat, Noushin, Hannoun, Zara, Tachdjian, Gérard, Melki, Judith, Dubart-Kupperschmitt, Anne
Format: Artigo
Idioma:Inglês
Publicat: AlphaMed Press 2015
Matèries:
Pluripotent Stem Cells
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339852/
https://ncbi.nlm.nih.gov/pubmed/25650439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2014-0186
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