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DNaseI Protects against Paraquat-Induced Acute Lung Injury and Pulmonary Fibrosis Mediated by Mitochondrial DNA

Background. Paraquat (PQ) poisoning is a lethal toxicological challenge that served as a disease model of acute lung injury and pulmonary fibrosis, but the mechanism is undetermined and no effective treatment has been discovered. Methods and Findings. We demonstrated that PQ injures mitochondria and...

詳細記述

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書誌詳細
出版年:Biomed Res Int
主要な著者: Li, Guo, Yuzhen, Li, Yi, Chen, Xiaoxiang, Chen, Wei, Zhou, Changqing, Zhu, Shuang, Ye
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi Publishing Corporation 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339792/
https://ncbi.nlm.nih.gov/pubmed/25759818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/386952
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