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The effect of rare variants on inflation of the test statistics in case–control analyses
BACKGROUND: The detection of bias due to cryptic population structure is an important step in the evaluation of findings of genetic association studies. The standard method of measuring this bias in a genetic association study is to compare the observed median association test statistic to the expec...
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| Publié dans: | BMC Bioinformatics |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4339749/ https://ncbi.nlm.nih.gov/pubmed/25888290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0496-1 |
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