Effective alignment of RNA pseudoknot structures using partition function posterior log-odds scores

BACKGROUND: RNA pseudoknots play important roles in many biological processes. Previous methods for comparative pseudoknot analysis mainly focus on simultaneous folding and alignment of RNA sequences. Little work has been done to align two known RNA secondary structures with pseudoknots taking into...

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Bibliographic Details
Published in:BMC Bioinformatics
Main Authors: Song, Yang, Hua, Lei, Shapiro, Bruce A, Wang, Jason TL
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
Subjects:
Methodology Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339682/
https://ncbi.nlm.nih.gov/pubmed/25727492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0464-9
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