Measuring semantic similarities by combining gene ontology annotations and gene co-function networks

BACKGROUND: Gene Ontology (GO) has been used widely to study functional relationships between genes. The current semantic similarity measures rely only on GO annotations and GO structure. This limits the power of GO-based similarity because of the limited proportion of genes that are annotated to GO...

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Bibliografiske detaljer
Udgivet i:BMC Bioinformatics
Main Authors: Peng, Jiajie, Uygun, Sahra, Kim, Taehyong, Wang, Yadong, Rhee, Seung Y, Chen, Jin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Methodology Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339680/
https://ncbi.nlm.nih.gov/pubmed/25886899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0474-7
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