Measuring semantic similarities by combining gene ontology annotations and gene co-function networks

BACKGROUND: Gene Ontology (GO) has been used widely to study functional relationships between genes. The current semantic similarity measures rely only on GO annotations and GO structure. This limits the power of GO-based similarity because of the limited proportion of genes that are annotated to GO...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Bioinformatics
Main Authors: Peng, Jiajie, Uygun, Sahra, Kim, Taehyong, Wang, Yadong, Rhee, Seung Y, Chen, Jin
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Methodology Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339680/
https://ncbi.nlm.nih.gov/pubmed/25886899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0474-7
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