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Measuring semantic similarities by combining gene ontology annotations and gene co-function networks

BACKGROUND: Gene Ontology (GO) has been used widely to study functional relationships between genes. The current semantic similarity measures rely only on GO annotations and GO structure. This limits the power of GO-based similarity because of the limited proportion of genes that are annotated to GO...

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Detalles Bibliográficos
Publicado en:BMC Bioinformatics
Main Authors: Peng, Jiajie, Uygun, Sahra, Kim, Taehyong, Wang, Yadong, Rhee, Seung Y, Chen, Jin
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339680/
https://ncbi.nlm.nih.gov/pubmed/25886899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0474-7
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