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Sites of Acetylation of Sickle Cell Hemoglobin by Aspirin

Aspirin acetylates a variety of sites on both the α and β chains of hemoglobin S. Nevertheless, the vast majority of acetyl groups become attached to three loci: βLys 59, βLys 144, and αLys 90. These observations reveal some molecular details of this transacylation reaction and suggest interesting p...

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Autori principali: Shamsuddin, Mir, Mason, R. George, Ritchey, James M., Honig, George R., Klotz, Irving M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1974
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC433962/
https://ncbi.nlm.nih.gov/pubmed/4531009
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