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Sites of Acetylation of Sickle Cell Hemoglobin by Aspirin

Aspirin acetylates a variety of sites on both the α and β chains of hemoglobin S. Nevertheless, the vast majority of acetyl groups become attached to three loci: βLys 59, βLys 144, and αLys 90. These observations reveal some molecular details of this transacylation reaction and suggest interesting p...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Shamsuddin, Mir, Mason, R. George, Ritchey, James M., Honig, George R., Klotz, Irving M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1974
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433962/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4531009/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.12.4693
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