Phosphatidylinositol 4,5-bisphosphate is an HCV NS5A Ligand and Mediates Replication of the Viral Genome

BACKGROUND & AIMS: Phosphoinositides (PIs) bind and regulate localization of proteins via a variety of structural motifs. PI 4,5-bisphosphate (PI[4,5]P(2)) interacts with and modulates the function of several proteins involved in intracellular vesicular membrane trafficking. We investigated inte...

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Bibliografiska uppgifter
I publikationen:Gastroenterology
Huvudupphovsmän: Cho, Nam-Joon, Lee, Choongho, Pang, Phillip S., Pham, Edward A., Fram, Benjamin, Nguyen, Khanh, Xiong, Anming, Sklan, Ella H., Elazar, Menashe, Koytak, Elif S., Kersten, Caroline, Kanazawa, Kay K., Frank, Curtis W., Glenn, Jeffrey S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339471/
https://ncbi.nlm.nih.gov/pubmed/25479136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.11.043
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