Phosphatidylinositol 4,5-bisphosphate is an HCV NS5A Ligand and Mediates Replication of the Viral Genome

BACKGROUND & AIMS: Phosphoinositides (PIs) bind and regulate localization of proteins via a variety of structural motifs. PI 4,5-bisphosphate (PI[4,5]P(2)) interacts with and modulates the function of several proteins involved in intracellular vesicular membrane trafficking. We investigated inte...

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Bibliografiske detaljer
Udgivet i:Gastroenterology
Main Authors: Cho, Nam-Joon, Lee, Choongho, Pang, Phillip S., Pham, Edward A., Fram, Benjamin, Nguyen, Khanh, Xiong, Anming, Sklan, Ella H., Elazar, Menashe, Koytak, Elif S., Kersten, Caroline, Kanazawa, Kay K., Frank, Curtis W., Glenn, Jeffrey S.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339471/
https://ncbi.nlm.nih.gov/pubmed/25479136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.11.043
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