Phosphatidylinositol 4,5-bisphosphate is an HCV NS5A Ligand and Mediates Replication of the Viral Genome

BACKGROUND & AIMS: Phosphoinositides (PIs) bind and regulate localization of proteins via a variety of structural motifs. PI 4,5-bisphosphate (PI[4,5]P(2)) interacts with and modulates the function of several proteins involved in intracellular vesicular membrane trafficking. We investigated inte...

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Detalhes bibliográficos
Publicado no:Gastroenterology
Main Authors: Cho, Nam-Joon, Lee, Choongho, Pang, Phillip S., Pham, Edward A., Fram, Benjamin, Nguyen, Khanh, Xiong, Anming, Sklan, Ella H., Elazar, Menashe, Koytak, Elif S., Kersten, Caroline, Kanazawa, Kay K., Frank, Curtis W., Glenn, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339471/
https://ncbi.nlm.nih.gov/pubmed/25479136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.11.043
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