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PD-1 suppresses protective immunity to Streptococcus pneumoniae through a B cell-intrinsic mechanism
Despite the emergence of the PD-1:PD-1 ligand (PD-L) regulatory axis as a promising target for treating multiple human diseases, remarkably little is known about how this pathway regulates responses to extracellular bacterial infections. We found that PD-1(−/−) mice, as well as wild type mice treate...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4339454/ https://ncbi.nlm.nih.gov/pubmed/25624454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401673 |
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