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Hyperglycemia diverts dividing stem cells to pathological adipogenesis

This commentary proposes a mechanism for why murine diabetic adipose tissue contains very few remaining stem cells compared with normal adipose tissue. The mechanism involves the diversion of stem cells to pathological adipocytes when they divide in hyperglycemia.

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Hascall, Vincent, Wang, Aimin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339424/
https://ncbi.nlm.nih.gov/pubmed/25689074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt518
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