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Joint Association Testing of Common and Rare Genetic Variants Using Hierarchical Modeling
New sequencing technologies provide an opportunity for assessing the impact of rare and common variants on complex diseases. Several methods have been developed for evaluating rare variants, many of which use weighted collapsing to combine rare variants. Some approaches require arbitrary frequency t...
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| Publicado en: | Genet Epidemiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4339046/ https://ncbi.nlm.nih.gov/pubmed/22807252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21659 |
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