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Population genetic simulations of complex phenotypes with implications for rare variant association tests
Demographic events and natural selection alter patterns of genetic variation within populations, and may play a substantial role in shaping the genetic architecture of complex phenotypes and disease. However, the joint impact of these basic evolutionary forces is often ignored in the assessment of s...
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| 出版年: | Genet Epidemiol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4270825/ https://ncbi.nlm.nih.gov/pubmed/25417809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21866 |
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