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Population genetics of rare variants and complex diseases

OBJECTIVES: Identifying drivers of complex traits from the noisy signals of genetic variation obtained from high throughput genome sequencing technologies is a central challenge faced by human geneticists today. We hypothesize that the variants involved in complex diseases are likely to exhibit non-...

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Main Authors: Maher, M. Cyrus, Uricchio, Lawrence H., Torgerson, Dara G., Hernandez, Ryan D.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698246/
https://ncbi.nlm.nih.gov/pubmed/23594490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000346826
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