Differential and opposing effects of imatinib on LPS- and ventilator-induced lung injury

Endothelial dysfunction underlies the pathophysiology of vascular disorders such as acute lung injury (ALI) syndromes. Recent work has identified the Abl family kinases (c-Abl and Arg) as important regulators of endothelial cell (EC) barrier function and suggests that their inhibition by currently a...

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發表在:Am J Physiol Lung Cell Mol Physiol
Main Authors: Letsiou, E., Rizzo, A. N., Sammani, S., Naureckas, P., Jacobson, J. R., Garcia, J. G. N., Dudek, S. M.
格式: Artigo
語言:Inglês
出版: American Physiological Society 2014
主題:
Call for Papers
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338930/
https://ncbi.nlm.nih.gov/pubmed/25480336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00323.2014
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