The Progressive Adaptation of a Georgian Isolate of African Swine Fever Virus to Vero Cells Leads to a Gradual Attenuation of Virulence in Swine Corresponding to Major Modifications of the Viral Genome

African swine fever virus (ASFV) causes a contagious and often lethal disease of feral and domestic swine. Experimental vaccines derived from naturally occurring, genetically modified, or cell culture-adapted ASFV have been evaluated, but no commercial vaccine is available to control African swine f...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Krug, Peter W., Holinka, Lauren G., O'Donnell, Vivian, Reese, Bo, Sanford, Brenton, Fernandez-Sainz, Ignacio, Gladue, Douglas P., Arzt, Jonathan, Rodriguez, Luis, Risatti, Guillermo R., Borca, Manuel V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338881/
https://ncbi.nlm.nih.gov/pubmed/25505073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03250-14
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