African Swine Fever Virus Georgia 2007 with a Deletion of Virulence-Associated Gene 9GL (B119L), when Administered at Low Doses, Leads to Virus Attenuation in Swine and Induces an Effective Protection against Homologous Challenge

African swine fever virus (ASFV) is the etiological agent of an often lethal disease of domestic pigs. Disease control strategies have been hampered by the unavailability of vaccines against ASFV. Since its introduction in the Republic of Georgia, a highly virulent virus, ASFV Georgia 2007 (ASFV-G),...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: O'Donnell, Vivian, Holinka, Lauren G., Krug, Peter W., Gladue, Douglas P., Carlson, Jolene, Sanford, Brenton, Alfano, Marialexia, Kramer, Edward, Lu, Zhiqiang, Arzt, Jonathan, Reese, Bo, Carrillo, Consuelo, Risatti, Guillermo R., Borca, Manuel V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524225/
https://ncbi.nlm.nih.gov/pubmed/26063424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00969-15
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