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Substitution of Specific Cysteine Residues in the E1 Glycoprotein of Classical Swine Fever Virus Strain Brescia Affects Formation of E1-E2 Heterodimers and Alters Virulence in Swine

E1, along with E(rns) and E2, is one of the three envelope glycoproteins of classical swine fever virus (CSFV). E1 and E2 are anchored to the virus envelope at their carboxyl termini, and E(rns) loosely associates with the viral envelope. In infected cells, E2 forms homodimers and heterodimers with...

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Detalhes bibliográficos
Main Authors: Fernández-Sainz, I., Holinka, L. G., Gladue, D., O'Donnell, V., Lu, Z., Gavrilov, B. K., Risatti, G. R., Borca, M. V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126598/
https://ncbi.nlm.nih.gov/pubmed/21561909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00186-11
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