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Hepatitis B Virus Core Protein Sensitizes Hepatocytes to Tumor Necrosis Factor-Induced Apoptosis by Suppression of the Phosphorylation of Mitogen-Activated Protein Kinase Kinase 7

Hepatitis B, which caused by hepatitis B virus (HBV) infection, remains a major health threat worldwide. Hepatic injury and regeneration from chronic inflammation are the main driving factors of liver fibrosis and cirrhosis in chronic hepatitis B. Proinflammatory tumor necrosis factor alpha (TNF-α)...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Jia, Baosen, Guo, Minggao, Li, Gaiyun, Yu, Demin, Zhang, Xinxin, Lan, Ke, Deng, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338861/
https://ncbi.nlm.nih.gov/pubmed/25428880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03106-14
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