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Nucleoporin Phosphorylation Triggered by the Encephalomyocarditis Virus Leader Protein Is Mediated by Mitogen-Activated Protein Kinases

Cardioviruses disrupt nucleocytoplasmic transport through the activity of their leader (L) protein. We have shown that hyperphosphorylation of nuclear pore proteins (nucleoporins or Nups), including Nup62, Nup153, and Nup214, is central to this L protein function and requires one or more cytosolic k...

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Bibliografski detalji
Glavni autori: Porter, Frederick W., Brown, Bradley, Palmenberg, Ann C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004318/
https://ncbi.nlm.nih.gov/pubmed/20881039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01484-09
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