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Nucleoporin Phosphorylation Triggered by the Encephalomyocarditis Virus Leader Protein Is Mediated by Mitogen-Activated Protein Kinases

Cardioviruses disrupt nucleocytoplasmic transport through the activity of their leader (L) protein. We have shown that hyperphosphorylation of nuclear pore proteins (nucleoporins or Nups), including Nup62, Nup153, and Nup214, is central to this L protein function and requires one or more cytosolic k...

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Detalhes bibliográficos
Main Authors: Porter, Frederick W., Brown, Bradley, Palmenberg, Ann C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004318/
https://ncbi.nlm.nih.gov/pubmed/20881039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01484-09
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