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Leader-Induced Phosphorylation of Nucleoporins Correlates with Nuclear Trafficking Inhibition by Cardioviruses

Picornaviruses disrupt nucleocytoplasmic trafficking pathways during infection. Poliovirus and rhinovirus inhibit nuclear protein import/export through a series of 2A protease-dependent cleavages within nuclear pore proteins (nucleoporins [Nups]), including Nup62, Nup98, and Nup153. Cardioviruses la...

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Detalhes bibliográficos
Main Authors: Porter, Frederick W., Palmenberg, Ann C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643766/
https://ncbi.nlm.nih.gov/pubmed/19073724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01752-08
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