Hepatitis B Virus Core Protein Sensitizes Hepatocytes to Tumor Necrosis Factor-Induced Apoptosis by Suppression of the Phosphorylation of Mitogen-Activated Protein Kinase Kinase 7

Hepatitis B, which caused by hepatitis B virus (HBV) infection, remains a major health threat worldwide. Hepatic injury and regeneration from chronic inflammation are the main driving factors of liver fibrosis and cirrhosis in chronic hepatitis B. Proinflammatory tumor necrosis factor alpha (TNF-α)...

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Bibliographic Details
Published in:J Virol
Main Authors: Jia, Baosen, Guo, Minggao, Li, Gaiyun, Yu, Demin, Zhang, Xinxin, Lan, Ke, Deng, Qiang
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338861/
https://ncbi.nlm.nih.gov/pubmed/25428880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03106-14
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