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Pyrrole Hydrogen Ionization of Imidazole Derivatives in Metal Ion Complexes and Carbonic Anhydrase

Zinc ion-induced pyrrole hydrogen ionization from a histidyl residue has recently been suggested as the source of the activity-related deprotonation in carbonic anhydrase (EC 4.2.1.1; carbonate hydro-lyase) occurring at pH 7-8. The results offered to support the hypothesis are shown to be deficient....

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Bibliographic Details
Main Author: Martin, R. Bruce
Format: Artigo
Language:Inglês
Published: 1974
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC433879/
https://ncbi.nlm.nih.gov/pubmed/4216018
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