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Pyrrole Hydrogen Ionization of Imidazole Derivatives in Metal Ion Complexes and Carbonic Anhydrase
Zinc ion-induced pyrrole hydrogen ionization from a histidyl residue has recently been suggested as the source of the activity-related deprotonation in carbonic anhydrase (EC 4.2.1.1; carbonate hydro-lyase) occurring at pH 7-8. The results offered to support the hypothesis are shown to be deficient....
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
1974
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC433879/ https://ncbi.nlm.nih.gov/pubmed/4216018 |
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