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Pyrrole Hydrogen Ionization of Imidazole Derivatives in Metal Ion Complexes and Carbonic Anhydrase

Zinc ion-induced pyrrole hydrogen ionization from a histidyl residue has recently been suggested as the source of the activity-related deprotonation in carbonic anhydrase (EC 4.2.1.1; carbonate hydro-lyase) occurring at pH 7-8. The results offered to support the hypothesis are shown to be deficient....

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Autor principal: Martin, R. Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433879/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4216018/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.11.4346
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