Phage-mediated Dispersal of Biofilm and Distribution of Bacterial Virulence Genes Is Induced by Quorum Sensing

The microbiome and the phage meta-genome within the human gut are influenced by antibiotic treatments. Identifying a novel mechanism, here we demonstrate that bacteria use the universal communication molecule AI-2 to induce virulence genes and transfer them via phage release. High concentrations (i....

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Udgivet i:PLoS Pathog
Main Authors: Rossmann, Friederike S., Racek, Tomas, Wobser, Dominique, Puchalka, Jacek, Rabener, Elaine M., Reiger, Matthias, Hendrickx, Antoni P. A., Diederich, Ann-Kristin, Jung, Kirsten, Klein, Christoph, Huebner, Johannes
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338201/
https://ncbi.nlm.nih.gov/pubmed/25706310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004653
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