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Compartmentalized protective and detrimental effects of endogenous MIF mediated by CXCR2 in a mouse model of myocardial ischemia/reperfusion
OBJECTIVES: Here we aimed to clarify the role of CXCR2 in the macrophage migration inhibitory factor (MIF)-mediated effects after myocardial ischemia and reperfusion (I/R). As a pleiotropic chemokine-like cytokine, MIF has been identified to activate multiple receptors including CD74 and CXCR2. In m...
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Publicado no: | Arterioscler Thromb Vasc Biol |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4337944/ https://ncbi.nlm.nih.gov/pubmed/23868943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.301633 |
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