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A Probabilistic Approach to Cooperativity of Ligand Binding by a Polyvalent Molecule

Cooperativity of ligand binding is defined operationally in terms of the Hill parameter n, whose values uniquely define the shape of the binding curve. When n is everywhere equal to 1 the system behaves as if the sites were all the same and independent. If at any point n is unequal to 1 the system i...

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Bibliografiske detaljer
Main Authors: Wyman, Jeffries, Phillipson, Paul E.
Format: Artigo
Sprog:Inglês
Udgivet: 1974
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC433787/
https://ncbi.nlm.nih.gov/pubmed/4530314
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